Trisomy X syndrome is a sex chromosome aneuploidy with a variable clinical presentation at different stages of life.We present two asyndromic females with primary infertility and features of premature ovarian failure (POF).The first case was a nonmosaic trisomy Shoe Care X with poor ovarian reserve on pelvic ultrasound and elevated gonadotropins, w

Tire-wear particles (TWPs) are being released into the environment by wearing down during car driving, and are considered an important microplastic pollution source.The chemical additive leaching from these polymer-based materials and its potential effects are likely temporally dynamic, since amounts of potentially toxic compounds can gradually inc

Retroviruses perpetuate their survival by incorporating a copy of their genome into the host cell, a critical step catalyzed by the virally encoded integrase.The viral capsid plays an important role during the viral life cycle, including nuclear importation in the case of lentiviruses and integration targeting events; hence, targeting the integrase